Commercial for Sale: 221 N Fifth Street, Hannibal, MO 63401

$439,000
$439,000
221 N Fifth Street, Hannibal, MO 63401
$439,000
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Price:
$439,000
Est. payment: Skip to Mortgage Calculator

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Type Commercial
Lot Size 0.21 acres
Year Built 1871
Taxes Paid $1,522
City Hannibal
County Marion
Subdivision Hannibal Original Town
MLS 26028895
Status Active
DOM 63 days
Step into a rare opportunity to own a true piece of Hannibal history with the iconic Dubach Inn—an elegant Italianate villa originally constructed in 1871 and offering nearly 5,000 square feet of finished living space. With the next owner becoming just the fifth owner in its 155 year history- The Dubach Inn represents a level of preservation and legacy that is rarely available. Ideally located just three blocks from Main Street in Hannibal’s historic downtown, the home blends timeless architectural character with modern comfort and exceptional income-producing potential. Currently operating as a successful bed and breakfast for 18 years, the property is designed with multiple private suite-style living spaces, each offering its own bedroom, sitting area, and bath—creating a layout that naturally supports a variety of uses. Two of the rear suites feature private exterior access, enhancing flexibility for short-term rentals, extended stays, or separate tenant use. The property is being sold fully furnished, allowing for a seamless transition for the next owner—whether continuing operations, launching a short-term rental business, or simply moving in and enjoying the space immediately. The nearly 5,000 square foot layout allows for a wide range of configurations, including owner-occupied living with separate rental spaces, group accommodations, or long-term housing options. Whether you choose to operate as a turnkey hospitality business, live in the home full-time while generating supplemental income, or convert the property into a high-performing short-term or multi-unit investment, the flexibility here is unmatched. Positioned in a tourism-driven market with steady visitors and returning guests, this property offers the rare combination of historic charm, prime location, and multiple income pathways—making the Dubach Inn both a legacy property and a forward-looking investment.

Lot & Building Features

Appliances Wall Oven, Gas Range, Stainless Steel Appliance(s), Refrigerator, Dishwasher
Construction Brick
Cooling Multi Units, Zoned, Central Air
Heating Zoned, Natural Gas, Forced Air
Parking Description On Street
Tax Year 2025
Taxes Paid $1,522
Water Public

Price History of 221 N Fifth Street, Hannibal, MO

Date Name Price Difference
05/09/2026 Listing Price $439,000 N/A
*Information provided by REWS for your reference only. The accuracy of this information cannot be verified and is not guaranteed.

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Photo of Steven Friedman
Office
3220 Pine Cliff Rd
Wildwood, MO 63038
314-616-9526
Listed by Christal Property Group, LLC, Madison Christal
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0.34669703872437%
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221 N Fifth Street (MLS #26028895) is a commercial listing located in Hannibal, MO. This is a commercial listing with a lot of 9,322 sqft (or 0.21 acres). This property was listed on 05/09/2026 and has been priced for sale at $439,000.

Nearby zip codes are 63459. This property neighbors other cities such as New London.

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Listing information courtesy of: Christal Property Group, LLC

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